NDAL NDAL

Suna and İnan Kıraç Foundation Neurodegeneration Research Laboratory (NDAL)

NDAL investigates the molecular mechanisms leading to progressive brain diseases such as Alzheimer's, Parkinson's, Huntington's, ALS and motor neuron disorders, ataxias, dystonias and movement disorders, myopathies and neuropathies in general. NDAL has established effective collaborations with all neurological units in Türkiye and has gained the trust of clinicians and centers across the country. With its well-trained team, deep-rooted knowledge and up-to-date infrastructure, NDAL has quickly become a pioneering and nationally visible reference center capable of diagnosing and researching progressive brain diseases at the molecular level.

Since 2005, NDAL has trained a large number of postdoctoral fellows, PhD students and graduate students. Currently, the lab’s team includes postdoctoral fellows; graduate students, including PhD and MSc students; two full-time administrative assistants; and two laboratory coordinators/technicians. The lab also provides research experience to undergraduate students on an ongoing basis.

In 2018, NDAL transferred from Boğaziçi University to Koç University School of Medicine. This transfer enabled the creation of strong collaboration between research scientists and clinicians, which has never been as critical and necessary as it is today. Since 2018, Koç University KUTTAM-NDAL has accelerated to become a center of excellence, with a distinguished patient cohort and large database, international collaborations, large-scale projects, and a well-trained and dedicated research team. The professional hospital environment of Koç University School of Medicine, a rising star that attracts the best students in Türkiye, is a significant contributing factor. With its Research Center for Translational Medicine (KUTTAM), Clinical Trials Unit (CTU), Center for Muscular Diseases and experienced Department of Neurology, Koç University provides NDAL with a unique opportunity to grow, deepen and remain sustainable. We believe that NDAL, with all these strong partnerships, will become a global leader in clinical research and elucidation of the mechanisms leading to neurodegenerative processes in the near future.

NDAL has filled an important gap in Türkiye with its state-of-the-art training of graduate students, original research published in high-impact scientific journals, and sophisticated and reliable molecular diagnostic services for complex neurological diseases.

NEWS

Latest news from NDAL

Dr. Fabiano Santos from IDRC Visits KUTTAM-NDAL
Dr. Fabiano Santos from IDRC Visits KUTTAM-NDAL
NDAL

Dr. Fabiano Santos from IDRC Visits KUTTAM-NDAL

Dr. Fabiano Santos, Senior Program Specialist at the Canada-based International Development Research Centre (IDRC), visited the NDAL team at Koç University Hospital on July 2, 2025.

Experts from Johns Hopkins and Harvard Visit Istanbul to Evaluate Children Diagnosed with AT
Experts from Johns Hopkins and Harvard Visit Istanbul to Evaluate Children Diagnosed with AT
NDAL

Experts from Johns Hopkins and Harvard Visit Istanbul to Evaluate Children Diagnosed with AT

Specialists from Johns Hopkins and Harvard Universities evaluated children diagnosed with Ataxia-Telangiectasia (AT), a rare genetic disorder, at healthcare institutions in Istanbul. This significant meeting marked a step forward in the potential application of advanced treatment methods in Turkey.

Exploring Genetic Inheritance: NDAL Hosts Prof. Houlden and Dr. Magrinelli
Exploring Genetic Inheritance: NDAL Hosts Prof. Houlden and Dr. Magrinelli
NDAL

Exploring Genetic Inheritance: NDAL Hosts Prof. Houlden and Dr. Magrinelli

From September 16-18, 2024, Professor Henry Houlden and Dr. Francesca Magrinelli from University College London (UCL) visited NDAL for an academic meeting and knowledge exchange. Over three intensive days, they examined 18 families, discussed genetic inheritance, and proposed Long Read Sequencing (LRS) for unresolved cases. This visit emphasized the importance of interdisciplinary collaboration in genetic research and provided a valuable model for future engagements.